Your Shopping Bag is Empty
ANTIOXIDANT

Superoxide Scavenging of Two Natural Products, Maharishi-4 [MAK-4] and Maharishi-5 [MAK-5]

Superoxide Scavenging of Two Natural Products, Maharishi-4 [MAK-4] and Maharishi-5 [MAK-5]

Publication
Federation of American Societies for Experimental Biology Journal, Vol. 5, No. 5, p. A1284, 1991 (Abstract).

Authors
Philip F. Tomlinson, Jr. and Robert Keith Wallace (SPON: J. Fagan).

Conducted at
Department of Physiological and Biological Sciences, Maharishi International University, Fairfield, IA 52556

Summary

Maharishi Ayurveda, a recent restoration of the traditional health care system of India, upholds an herbal fruit concentrate (M-4) and an herbal tablet (M-5) as rasayanas—food supplements that promote physiological balance, health, and immunity. The superoxide scavenging properties of M-4, M-5, and ascorbic acid were investigated with superoxide radicals generated during the catalytic activity of xanthine oxidase. M-4 and M-5 (10 mg/ml prior to centrifugation) inhibited the reduction of nitroblue tetrazolium (NBT) 98% and 96%, respectively. 50% inhibition of NBT reduction was obtained with 0.04 mg/ml M-4 and 0.15 mg/ml M-5. Ascorbic acid inhibition of superoxide radical reduction of NBT reached 88% at 1 mM, but declined to 42% at a concentration of 10 mM. The rate of uric acid production monitored at 290 nm demonstrated negligible inhibition of xanthine oxidase by M-4, M-5, or ascorbic acid. The results contribute to an understanding of previously reported antineoplastic, antioxidant, and anti-aging properties of M-4 and M-5, and warrant consideration in the light of present preventive, nutritional, and chemotherapeutic approaches to health, antioxidant defense, and carcinogenesis.

Please Note

MAK-4 is now called Amrit Kalash Nectar.
MAK-5 is now called Amrit Kalash Ambrosia.




© 1999, 2021 Maharishi AyurVeda Products International, Inc. (MAPI). All Rights Reserved. MAPI does not provide medical advice, diagnosis or treatment. These statements have not been evaluated by the Food and Drug Administration. Products are not intended to diagnose, treat, cure or prevent any disease. See additional information.